Characterization of the Genomic Xist Locus in Rodents Reveals Conservation of Overall Gene Structure and Tandem Repeats but Rapid Evolution of Unique Sequence

The Xist locus plays a central role in the regulation of X chromosome inactivation in mammals, although its exact mode of action remains to be elucidated. Evolutionary studies are important in identifying conserved genomic regions and defining their possible function. Here we report cloning, sequenc...

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Bibliografiske detaljer
Main Authors: Nesterova, Tatyana B., Slobodyanyuk, Sergey Ya., Elisaphenko, Eugene A., Shevchenko, Alexander I., Johnston, Colette, Pavlova, Marina E., Rogozin, Igor B., Kolesnikov, Nikolay N., Brockdorff, Neil, Zakian, Suren M.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2001
Fag:
Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC311126/
https://ncbi.nlm.nih.gov/pubmed/11337478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.174901
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