YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing
Abstract X chromosome inactivation (XCI) in mammals is mediated by Xist RNA which functions in cis to silence genes on a single X chromosome in XX female cells, thereby equalising levels of X-linked gene expression relative to XY males. XCI progresses over a period of several days, with some X-linke...
Furkejuvvon:
| Váldodahkkit: | , , , |
|---|---|
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Springer Nature
2024-04-01
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| Ráidu: | EMBO Reports |
| Fáttát: | |
| Liŋkkat: | https://doi.org/10.1038/s44319-024-00136-3 |
| Fáddágilkorat: |
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