Characterization of the Genomic Xist Locus in Rodents Reveals Conservation of Overall Gene Structure and Tandem Repeats but Rapid Evolution of Unique Sequence

The Xist locus plays a central role in the regulation of X chromosome inactivation in mammals, although its exact mode of action remains to be elucidated. Evolutionary studies are important in identifying conserved genomic regions and defining their possible function. Here we report cloning, sequenc...

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Autors principals: Nesterova, Tatyana B., Slobodyanyuk, Sergey Ya., Elisaphenko, Eugene A., Shevchenko, Alexander I., Johnston, Colette, Pavlova, Marina E., Rogozin, Igor B., Kolesnikov, Nikolay N., Brockdorff, Neil, Zakian, Suren M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2001
Matèries:
Letter
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC311126/
https://ncbi.nlm.nih.gov/pubmed/11337478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.174901
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