Characterization of the Genomic Xist Locus in Rodents Reveals Conservation of Overall Gene Structure and Tandem Repeats but Rapid Evolution of Unique Sequence

The Xist locus plays a central role in the regulation of X chromosome inactivation in mammals, although its exact mode of action remains to be elucidated. Evolutionary studies are important in identifying conserved genomic regions and defining their possible function. Here we report cloning, sequenc...

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Autori principali: Nesterova, Tatyana B., Slobodyanyuk, Sergey Ya., Elisaphenko, Eugene A., Shevchenko, Alexander I., Johnston, Colette, Pavlova, Marina E., Rogozin, Igor B., Kolesnikov, Nikolay N., Brockdorff, Neil, Zakian, Suren M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2001
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Letter
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC311126/
https://ncbi.nlm.nih.gov/pubmed/11337478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.174901
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