Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients

BACKGROUND: Epidermal growth factor receptor (EGFR) promoter methylation may be responsible for the loss of EGFR expression in neoplastic cells. The primary aim of our study was to verify a possible correlation between EGFR gene promoter methylation and clinical outcome in metastatic colorectal canc...

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Detalhes bibliográficos
Main Authors: Scartozzi, M, Bearzi, I, Mandolesi, A, Giampieri, R, Faloppi, L, Galizia, E, Loupakis, F, Zaniboni, A, Zorzi, F, Biscotti, T, Labianca, R, Falcone, A, Cascinu, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111171/
https://ncbi.nlm.nih.gov/pubmed/21559018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.161
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