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Context-Specific Growth Hormone Signaling through the Transcription Factor STAT5: Implications for the Etiology of Hepatosteatosis and Hepatocellular Carcinoma
Growth hormone (GH) controls hepatic physiology to a large extent through the transcription factor signal transducers and activators of transcription (STAT) 5. Here, we focus on lessons learned from the physiology and pathophysiology of mice with disrupted Ghr and Stat5 loci. We discuss that hepatos...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publications
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111010/ https://ncbi.nlm.nih.gov/pubmed/21779476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911405046 |
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