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Context-Specific Growth Hormone Signaling through the Transcription Factor STAT5: Implications for the Etiology of Hepatosteatosis and Hepatocellular Carcinoma

Growth hormone (GH) controls hepatic physiology to a large extent through the transcription factor signal transducers and activators of transcription (STAT) 5. Here, we focus on lessons learned from the physiology and pathophysiology of mice with disrupted Ghr and Stat5 loci. We discuss that hepatos...

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Detalhes bibliográficos
Main Authors: Yoo, Kyung Hyun, Baik, Myunggi, Hennighausen, Lothar
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111010/
https://ncbi.nlm.nih.gov/pubmed/21779476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911405046
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