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Methionine synthase reductase deficiency results in adverse reproductive outcomes and congenital heart defects in mice

Low dietary folate and polymorphisms in genes of folate metabolism can influence risk for pregnancy complications and birth defects. Methionine synthase reductase (MTRR) is required for activation of methionine synthase, a folate- and vitamin B(12)-dependent enzyme. A polymorphism in MTRR (p.I22M),...

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Detalhes bibliográficos
Main Authors: Deng, Liyuan, Elmore, C. Lee, Lawrance, Andrea K., Matthews, Rowena G., Rozen, Rima
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110750/
https://ncbi.nlm.nih.gov/pubmed/18413293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2008.03.004
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