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Methionine synthase reductase deficiency results in adverse reproductive outcomes and congenital heart defects in mice
Low dietary folate and polymorphisms in genes of folate metabolism can influence risk for pregnancy complications and birth defects. Methionine synthase reductase (MTRR) is required for activation of methionine synthase, a folate- and vitamin B(12)-dependent enzyme. A polymorphism in MTRR (p.I22M),...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110750/ https://ncbi.nlm.nih.gov/pubmed/18413293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2008.03.004 |
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