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Polymorphisms in Methionine Synthase Reductase and Betaine-Homocysteine S-Methyltransferase Genes: Risk of Placental Abruption

OBJECTIVE: Methionine Synthase Reductase (MTRR) and Betaine-Homocysteine S-Methyltransferase (BHMT) are 2 enzymes that regulate homocysteine metabolism. Elevated homocysteine (hyperhomocysteinemia) is associated with adverse pregnancy outcomes and vascular disease. We assessed whether polymorphisms...

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Autori principali: Ananth, Cande V., Elsasser, Denise, Kinzler, Wendy L., Peltier, Morgan R., Getahun, Darios, Leclerc, Daniel, Rozen, Rima R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885454/
https://ncbi.nlm.nih.gov/pubmed/17376725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2007.02.004
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