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Activation of Methyltetrahydrofolate by Cobalamin-Independent Methionine Synthase

Cobalamin-independent methionine synthase (MetE) catalyzes the final step of de novo methionine synthesis using the triglutamate derivative of methyltetrahydrofolate (CH(3)-H(4)PteGlu(3)) as methyl donor and homocysteine (Hcy) as methyl acceptor. This reaction is challenging because at physiological...

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Detalhes bibliográficos
Main Authors: Taurog, Rebecca E., Matthews, Rowena G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041922/
https://ncbi.nlm.nih.gov/pubmed/16618098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060052m
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