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Synergistic, Random Sequential Binding of Substrates in Cobalamin-Independent Methionine Synthase

Cobalamin-independent methionine synthase (MetE) catalyzes the transfer of the N5-methyl group of methyltetrahydrofolate (CH(3)-H(4)folate) to the sulfur of homocysteine (Hcy) to form methionine and tetrahydrofolate (H(4)folate) as products. This reaction is thought to involve a direct methyl transf...

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Detalhes bibliográficos
Main Authors: Taurog, Rebecca E., Jakubowski, Hieronim, Matthews, Rowena G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041902/
https://ncbi.nlm.nih.gov/pubmed/16618097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060051u
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