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LXR as a novel antithrombotic target

Liver X receptors (LXRs) are transcription factors involved in the regulation of cholesterol homeostasis. LXR ligands have athero-protective properties independent of their effects on cholesterol metabolism. Platelets are involved in the initiation of atherosclerosis and despite being anucleate expr...

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Autores principales: Spyridon, Michael, Moraes, Leonardo A., Jones, Chris I., Sage, Tanya, Sasikumar, Parvathy, Bucci, Giovanna, Gibbins, Jonathan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110032/
https://ncbi.nlm.nih.gov/pubmed/21411760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-306142
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