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3-Alkoxy-1,2-Dioxolanes: Synthesis and Evaluation as Potential Antimalarial Agents

[Image: see text] A number of 3-alkoxy-1,2-dioxolanes exhibit promising levels of antimalarial activity against Plasmodium falciparum. A new route to the 1,2-dioxolane core is reported based on tandem peroxidation/cyclization of enones.

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Detalhes bibliográficos
Main Authors: Schiaffo, Charles E., Rottman, Matthias, Wittlin, Sergio, Dussault, Patrick H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109996/
https://ncbi.nlm.nih.gov/pubmed/21666827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100308d
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