In vitro and in vivo activity of 3-alkoxy-1,2-dioxolanes against Schistosoma mansoni

OBJECTIVES: Compounds characterized by a peroxidic skeleton are an interesting starting point for antischistosomal drug discovery. Previously a series of 3-alkoxy-1,2-dioxolanes, which are chemically stable cyclic peroxides, demonstrated significant in vitro activity against Plasmodium falciparum. W...

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Detaylı Bibliyografya
Asıl Yazarlar: Ingram, Katrin, Schiaffo, Charles E., Sittiwong, Wantanee, Benner, Evan, Dussault, Patrick H., Keiser, Jennifer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394440/
https://ncbi.nlm.nih.gov/pubmed/22553141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dks141
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