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Multimeric assembly and biochemical characterization of the Trax/Translin endonuclease complex

Trax/Translin heteromers, also known as C3PO, have been proposed to activate RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand. We report on the crystal structure of hexameric Drosophila C3PO formed by truncated Translin and Trax, along with...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Tian, Yuan, Simanshu, Dhirendra K., Ascano, Manuel, Diaz-Avalos, Ruben, Park, Ah Young, Juranek, Stefan A., Rice, William J., Yin, Qian, Robinson, Carol V., Tuschl, Thomas, Patel, Dinshaw J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109869/
https://ncbi.nlm.nih.gov/pubmed/21552261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2069
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