Multimeric assembly and biochemical characterization of the Trax/Translin endonuclease complex

Trax/Translin heteromers, also known as C3PO, have been proposed to activate RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand. We report on the crystal structure of hexameric Drosophila C3PO formed by truncated Translin and Trax, along with...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Tian, Yuan, Simanshu, Dhirendra K., Ascano, Manuel, Diaz-Avalos, Ruben, Park, Ah Young, Juranek, Stefan A., Rice, William J., Yin, Qian, Robinson, Carol V., Tuschl, Thomas, Patel, Dinshaw J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109869/
https://ncbi.nlm.nih.gov/pubmed/21552261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2069
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы