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Multimeric assembly and biochemical characterization of the Trax/Translin endonuclease complex
Trax/Translin heteromers, also known as C3PO, have been proposed to activate RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand. We report on the crystal structure of hexameric Drosophila C3PO formed by truncated Translin and Trax, along with...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109869/ https://ncbi.nlm.nih.gov/pubmed/21552261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2069 |
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