Multimeric assembly and biochemical characterization of the Trax/Translin endonuclease complex

Trax/Translin heteromers, also known as C3PO, have been proposed to activate RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand. We report on the crystal structure of hexameric Drosophila C3PO formed by truncated Translin and Trax, along with...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Tian, Yuan, Simanshu, Dhirendra K., Ascano, Manuel, Diaz-Avalos, Ruben, Park, Ah Young, Juranek, Stefan A., Rice, William J., Yin, Qian, Robinson, Carol V., Tuschl, Thomas, Patel, Dinshaw J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109869/
https://ncbi.nlm.nih.gov/pubmed/21552261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2069
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars