Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies

LMO2 is a target of chromosomal translocations in T-cell tumors and was activated by retroviral vector insertions in T-cell tumors from X-SCID patients in gene therapy trials. To better understand the cooperating genetic events in LMO2-associated T-cell acute lymphoblastic leukemia (T-ALL), we inves...

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Bibliografiska uppgifter
Huvudupphovsmän: Treanor, Louise M., Volanakis, Emmanuel J., Zhou, Sheng, Lu, Taihe, Sherr, Charles J., Sorrentino, Brian P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2011
Ämnen:
Lymphoid Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109717/
https://ncbi.nlm.nih.gov/pubmed/21427293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-309831
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