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Stage-specific Arf tumor suppression in Notch1-induced T-cell acute lymphoblastic leukemia
Frequent hallmarks of T-cell acute lymphoblastic leukemia (T-ALL) include aberrant NOTCH signaling and deletion of the CDKN2A locus, which contains 2 closely linked tumor suppressor genes (INK4A and ARF). When bone marrow cells or thymocytes transduced with a vector encoding the constitutively activ...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777126/ https://ncbi.nlm.nih.gov/pubmed/19759355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-233346 |
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