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N-terminal polyubiquitination and degradation of the Arf tumor suppressor
Unknown mechanisms govern degradation of the p19(Arf) tumor suppressor, an activator of p53 and inhibitor of ribosomal RNA processing. Kinetic metabolic labeling of cells with [(3)H]-leucine indicated that p19(Arf) is a relatively stable protein (half-life ∼6 h) whose degradation depends upon the ub...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC517406/ https://ncbi.nlm.nih.gov/pubmed/15289458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1213904 |
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