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Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies
LMO2 is a target of chromosomal translocations in T-cell tumors and was activated by retroviral vector insertions in T-cell tumors from X-SCID patients in gene therapy trials. To better understand the cooperating genetic events in LMO2-associated T-cell acute lymphoblastic leukemia (T-ALL), we inves...
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Главные авторы: | , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
American Society of Hematology
2011
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109717/ https://ncbi.nlm.nih.gov/pubmed/21427293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-309831 |
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