HIV-specific CD8(+) T cells from HIV(+) individuals receiving HAART can be expanded ex vivo to augment systemic and mucosal immunity in vivo

Most HIV(+) individuals require lifelong highly active antiretroviral therapy (HAART) to suppress HIV replication, but fail to eliminate the virus in part because of residual replication in gut-associated lymphoid tissues (GALT). Naturally elicited HIV-specific CD8(+) T cells generated in the acute...

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Autors principals: Chapuis, Aude G., Casper, Corey, Kuntz, Steve, Zhu, Jia, Tjernlund, Annelie, Diem, Kurt, Turtle, Cameron J., Cigal, Melinda L., Velez, Roxanne, Riddell, Stanley, Corey, Lawrence, Greenberg, Philip D.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109713/
https://ncbi.nlm.nih.gov/pubmed/21422474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-320226
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