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HIV-specific cytotoxic T lymphocytes traffic to lymph nodes and localize at sites of HIV replication and cell death

We have tracked the in vivo migration and have identified in vivo correlates of cytotoxic T-lymphocyte (CTL) activity in HIV-seropositive subjects infused with autologous gene-marked CD8(+) HIV-specific CTL. The number of circulating gene-marked CTL ranged from 1.6 to 3.5% shortly after infusion to...

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Detalhes bibliográficos
Main Authors: Brodie, Scott J., Patterson, Bruce K., Lewinsohn, Deborah A., Diem, Kurt, Spach, David, Greenberg, Phillip D., Riddell, Stanley R., Corey, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC315465/
https://ncbi.nlm.nih.gov/pubmed/10811848
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