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Self MHC class I–licensed NK cells enhance adaptive CD8 T-cell viral immunity

MHC class I (MHC I) is essential to NK- and T-cell effector and surveillance functions. However, it is unknown whether MHC I polymorphism influences adaptive immunity through NK cells. Previously, we found that MHC I D(k), a cognate ligand for the Ly49G2 inhibitory receptor, was essential to NK cont...

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Detalhes bibliográficos
Main Authors: Stadnisky, Michael D., Xie, Xuefang, Coats, Ebony R., Bullock, Timothy N., Brown, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109538/
https://ncbi.nlm.nih.gov/pubmed/21436069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-324632
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