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Multi-parametric analysis of host response to murine CMV in MHC class I disparate mice reveals primacy of D(k)-licensed Ly49G(2)+ NK cells in viral control, 3
MHC I D(k) and Ly49G(2) inhibitory receptor-expressing NK cells are essential to murine (M)CMV() resistance in MA/My mice. Without D(k), Ly49G(2)+ NK cells in C57L mice fail to protect against MCMV infection. As a cognate ligand of Ly49G(2), D(k) licenses Ly49G(2)+ NK cells for effector activity. Th...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820117/ https://ncbi.nlm.nih.gov/pubmed/24068668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301388 |
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