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Innate Immune Recognition of Francisella Tularensis: Activation of Type-I Interferons and the Inflammasome

Francisella tularensis is an intracellular pathogen that can cause severe disease in a wide range of mammalian hosts. Primarily residing in host macrophages, F. tularensis escapes phagosomal degradation, and replicates in the macrophage cytosol. The macrophage uses a series of pattern recognition re...

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Autors principals: Jones, Jonathan Wiley, Broz, Petr, Monack, Denise M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109290/
https://ncbi.nlm.nih.gov/pubmed/21687410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2011.00016
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