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Innate Immune Recognition of Francisella Tularensis: Activation of Type-I Interferons and the Inflammasome
Francisella tularensis is an intracellular pathogen that can cause severe disease in a wide range of mammalian hosts. Primarily residing in host macrophages, F. tularensis escapes phagosomal degradation, and replicates in the macrophage cytosol. The macrophage uses a series of pattern recognition re...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Research Foundation
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109290/ https://ncbi.nlm.nih.gov/pubmed/21687410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2011.00016 |
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