Loss of Heterozygosity Assay for Molecular Detection of Cancer Using Energy-transfer Primers and Capillary Array Electrophoresis

Microsatellite DNA loci are useful markers for the detection of loss of heterozygosity (LOH) and microsatellite instability (MI) associated with primary cancers. To carry out large-scale studies of LOH and MI in cancer progression, high-throughput instrumentation and assays with high accuracy and se...

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Pubblicato in:	Genome Res
Autori principali:	Medintz, Igor L., Lee, Chyi-Chia Richard, Wong, Wendy W., Pirkola, Kristin, Sidransky, David, Mathies, Richard A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2000
Soggetti:	Methods
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10958639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.10.8.1211
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