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Loss of Heterozygosity Assay for Molecular Detection of Cancer Using Energy-transfer Primers and Capillary Array Electrophoresis

Microsatellite DNA loci are useful markers for the detection of loss of heterozygosity (LOH) and microsatellite instability (MI) associated with primary cancers. To carry out large-scale studies of LOH and MI in cancer progression, high-throughput instrumentation and assays with high accuracy and se...

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Bibliografiske detaljer
Udgivet i:Genome Res
Principais autores: Medintz, Igor L., Lee, Chyi-Chia Richard, Wong, Wendy W., Pirkola, Kristin, Sidransky, David, Mathies, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10958639/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.10.8.1211
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