Loss of Heterozygosity Assay for Molecular Detection of Cancer Using Energy-transfer Primers and Capillary Array Electrophoresis

Microsatellite DNA loci are useful markers for the detection of loss of heterozygosity (LOH) and microsatellite instability (MI) associated with primary cancers. To carry out large-scale studies of LOH and MI in cancer progression, high-throughput instrumentation and assays with high accuracy and se...

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Veröffentlicht in:	Genome Res
Hauptverfasser:	Medintz, Igor L., Lee, Chyi-Chia Richard, Wong, Wendy W., Pirkola, Kristin, Sidransky, David, Mathies, Richard A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 2000
Schlagworte:	Methods
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10958639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.10.8.1211
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