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Mapping the orientation of nuclear pore proteins in living cells with polarized fluorescence microscopy
The nuclear pore complex (NPC) perforates the nuclear envelope to facilitate selective transport between nucleus and cytoplasm. The NPC is composed of multiple copies of ~30 different proteins, termed nucleoporins, whose arrangement within the NPC is a major unsolved puzzle in structural biology. Va...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109191/ https://ncbi.nlm.nih.gov/pubmed/21499242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2056 |
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