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Novel Role of Mitochondrial Matrix Metalloproteinase-2 in the Development of Diabetic Retinopathy
PURPOSE. In the pathogenesis of diabetic retinopathy, retinal mitochondria become dysfunctional, their DNA is damaged, and capillary cells undergo accelerated apoptosis. Matrix metalloproteinase-2 (MMP2) becomes activated and proapoptotic, and the therapies that inhibit the development of diabetic r...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109059/ https://ncbi.nlm.nih.gov/pubmed/21345984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6368 |
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