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Novel Role of Mitochondrial Matrix Metalloproteinase-2 in the Development of Diabetic Retinopathy

PURPOSE. In the pathogenesis of diabetic retinopathy, retinal mitochondria become dysfunctional, their DNA is damaged, and capillary cells undergo accelerated apoptosis. Matrix metalloproteinase-2 (MMP2) becomes activated and proapoptotic, and the therapies that inhibit the development of diabetic r...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Mohammad, Ghulam, Kowluru, Renu A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Association for Research in Vision and Ophthalmology, Inc. 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109059/
https://ncbi.nlm.nih.gov/pubmed/21345984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6368
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