Engagement of TLR2 Reverses the Suppressor Function of Conjunctiva CD4(+)CD25(+) Regulatory T Cells and Promotes Herpes Simplex Virus Epitope-Specific CD4(+)CD25(−) Effector T Cell Responses

PURPOSE. The authors recently reported that Foxp3(+)CD4(+) CD25(+(Bright)) “natural” regulatory T cells (nT(reg) cells) are abundant in rabbit conjunctiva and suppress herpes simplex virus (HSV)-1–specific CD4(+) and CD8(+) effector T cells (T(eff) cells). However, little is known about the overall...

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Detalhes bibliográficos
Main Authors: Dasgupta, Gargi, Chentoufi, Aziz Alami, You, Sylvaine, Falatoonzadeh, Payam, Urbano, Lourie Ann A., Akhtarmalik, Ayesha, Nguyen, Kimberly, Ablabutyan, Lilit, Nesburn, Anthony B., BenMohamed, Lbachir
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109031/
https://ncbi.nlm.nih.gov/pubmed/21273544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6522
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