Functional Foxp3(+) CD4(+) CD25((Bright+)) “Natural” Regulatory T Cells Are Abundant in Rabbit Conjunctiva and Suppress Virus-Specific CD4(+) and CD8(+) Effector T Cells during Ocular Herpes Infection

We studied the phenotype and distribution of “naturally” occurring CD4(+) CD25(+) T regulatory cells (CD4(+) CD25(+) nT(reg) cells) resident in rabbit conjunctiva, the main T-cell inductive site of the ocular mucosal immune system, and we investigated their suppressive capacities using herpes simple...

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Autores principales: Nesburn, Anthony B., Bettahi, Ilham, Dasgupta, Gargi, Chentoufi, Alami Aziz, Zhang, Xiuli, You, Sylvaine, Morishige, Naoyuki, Wahlert, Andrew J., Brown, Donald J., Jester, James V., Wechsler, Steven L., BenMohamed, Lbachir
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933381/
https://ncbi.nlm.nih.gov/pubmed/17475646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00294-07
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