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Association Between Nuclear Lamin A/C R482Q Mutation and Partial Lipodystrophy with Hyperinsulinemia, Dyslipidemia, Hypertension, and Diabetes

Nuclear lamins A and C are encoded by LMNA and are present in terminally differentiated cells. Lamins participate in DNA replication, chromatin organization, arrangement of nuclear pores, nuclear growth, and anchorage of nuclear membranes. In several Canadian probands with partial lipodystrophy, sin...

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Bibliografske podrobnosti
izdano v:Genome Res
Main Authors: Hegele, Robert A., Anderson, Carol M., Wang, Jian, Jones, Doreen C., Cao, Henian
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2000
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310873/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10810087/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.10.5.652
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