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Structure of the lamin A/C R482W mutant responsible for dominant familial partial lipodystrophy (FPLD)

Proteins of the A-type lamin family, which consists of two members, lamin A and lamin C, are the major components of a thin proteinaceous filamentous meshwork, the lamina, that underlies the inner nuclear membrane. A-type lamins have recently become the focus of extensive functional studies as a con...

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Détails bibliographiques
Auteurs principaux: Magracheva, Eugenia, Kozlov, Serguei, Stewart, Colin L., Wlodawer, Alexander, Zdanov, Alexander
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705630/
https://ncbi.nlm.nih.gov/pubmed/19574635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109020302
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