Hyperforin, an Anti-Inflammatory Constituent from St. John's Wort, Inhibits Microsomal Prostaglandin E(2) Synthase-1 and Suppresses Prostaglandin E(2) Formation in vivo

The acylphloroglucinol hyperforin (Hyp) from St. John's wort possesses anti-inflammatory and anti-carcinogenic properties which were ascribed among others to the inhibition of 5-lipoxygenase. Here, we investigated whether Hyp also interferes with prostanoid generation in biological systems, par...

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Bibliografiske detaljer
Main Authors: Koeberle, Andreas, Rossi, Antonietta, Bauer, Julia, Dehm, Friederike, Verotta, Luisella, Northoff, Hinnak, Sautebin, Lidia, Werz, Oliver
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Research Foundation 2011
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108608/
https://ncbi.nlm.nih.gov/pubmed/21687502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2011.00007
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