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Inhibition of microsomal prostaglandin E(2) synthase-1 as a molecular basis for the anti-inflammatory actions of boswellic acids from frankincense

BACKGROUND AND PURPOSE: Frankincense, the gum resin derived from Boswellia species, showed anti-inflammatory efficacy in animal models and in pilot clinical studies. Boswellic acids (BAs) are assumed to be responsible for these effects but their anti-inflammatory efficacy in vivo and their molecular...

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Detalhes bibliográficos
Main Authors: Siemoneit, U, Koeberle, A, Rossi, A, Dehm, F, Verhoff, M, Reckel, S, Maier, TJ, Jauch, J, Northoff, H, Bernhard, F, Doetsch, V, Sautebin, L, Werz, O
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012413/
https://ncbi.nlm.nih.gov/pubmed/20840544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01020.x
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