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Congenic Mapping of the Type 1 Diabetes Locus, Idd3, to a 780-kb Region of Mouse Chromosome 3: Identification of a Candidate Segment of Ancestral DNA by Haplotype Mapping

Type 1 diabetes in the nonobese diabetic (NOD) mouse arises as a consequence of T cell-mediated destruction of the insulin-producing β cells of the pancreas. Although little is known of the events that initiate and subsequently drive β-cell destruction it is clear that the entire process is under co...

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Detalhes bibliográficos
Main Authors: Lyons, Paul A., Armitage, Nicola, Argentina, Fabio, Denny, Paul, Hill, Natasha J., Lord, Christopher J., Wilusz, Mary Beth, Peterson, Laurence B., Wicker, Linda S., Todd, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC310860/
https://ncbi.nlm.nih.gov/pubmed/10779485
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