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Identification of a new malaria susceptibility locus (Char4) in recombinant congenic strains of mice

The genetic component of susceptibility to malaria is complex, both in humans and in the mouse model of infection. Two murine loci on chromosomes 8 (Pchr/Char2) and 9 (Char1) have previously been mapped in F(2) crosses, and play an important role in regulating blood parasitemia and survival to infec...

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Detalhes bibliográficos
Main Authors: Fortin, Anny, Cardon, Lon R., Tam, Mifong, Skamene, Emil, Stevenson, Mary M., Gros, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC58554/
https://ncbi.nlm.nih.gov/pubmed/11535821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191288998
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