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MIM and Cortactin antagonism regulates ciliogenesis and Hedgehog signaling

The primary cilium is critical for transducing Sonic hedgehog (Shh) signaling, but the mechanisms of its transient assembly are poorly understood. Previously we showed that the actin regulatory protein Missing-in-Metastasis (MIM) regulates Shh signaling, but the nature of MIM’s role was unknown. Her...

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Autori principali: Bershteyn, Marina, Atwood, Scott X, Woo, Wei Meng, Li, Mischa, Oro, Anthony E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108505/
https://ncbi.nlm.nih.gov/pubmed/20708589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.07.009
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