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Effects of Manganese on Tyrosine Hydroxylase (TH) Activity and TH-phosphorylation in a Dopaminergic Neural Cell Line

Manganese (Mn) exposure causes manganism, a neurological disorder similar to Parkinson’s disease. However, the cellular mechanism by which Mn impairs the dopaminergic neurotransmitter system remains unclear. We previously demonstrated that caspase-3-dependent proteolytic activation of protein kinase...

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Autors principals: Zhang, Danhui, Kanthasamy, Arthi, Anantharam, Vellareddy, Kanthasamy, Anumantha
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107879/
https://ncbi.nlm.nih.gov/pubmed/21310168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.03.023
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