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An Automated Hydrodynamic Process for Controlled, Unbiased DNA Shearing

An automated, inexpensive, easy-to-use, and reproducible technique for controlled, random DNA fragmentation has been developed. The technique is based on point–sink hydrodynamics that result when a DNA sample is forced through a small hole by a syringe pump. Commercially available components are use...

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Detalhes bibliográficos
Main Authors: Thorstenson, Yvonne R., Hunicke-Smith, Scott P., Oefner, Peter J., Davis, Ronald W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC310760/
https://ncbi.nlm.nih.gov/pubmed/9724331
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