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The Use of Chromatin Insulators to Improve the Expression and Safety of Integrating Gene Transfer Vectors

The therapeutic application of recombinant retroviruses and other integrating gene transfer vectors has been limited by problems of vector expression and vector-mediated genotoxicity. These problems arise in large part from the interactions between vector sequences and the genomic environment surrou...

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Bibliografski detalji
Glavni autor: Emery, David W.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107579/
https://ncbi.nlm.nih.gov/pubmed/21247248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.233
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