Mosaic analysis of insulin receptor function

Insulin promotes both metabolism and growth. However, it is unclear whether insulin-dependent growth is merely a result of its metabolic actions. Targeted ablation of insulin receptor (Insr) has not clarified this issue, because of early postnatal lethality. To examine this question, we generated mi...

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Hlavní autoři: Kitamura, Tadahiro, Kitamura, Yukari, Nakae, Jun, Giordano, Antonio, Cinti, Saverio, Kahn, C. Ronald, Efstratiadis, Argiris, Accili, Domenico
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC310748/
https://ncbi.nlm.nih.gov/pubmed/14722613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200417810
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