Expression, Purification and Characterization of A Novel Soluble Human Thymosin Alpha1 Concatemer Exhibited A Stronger Stimulation on Mice Lymphocytes Proliferation and Higher Anti-tumor Activity

Thymosin alpha 1 (Tα1) has immunomodulatory and anti-tumor effects in patients and has been commercialized in worldwide. An innovative technique is therefore impending to achieve high-yield expression and purification of Tα1 to meet the increasing requirements for clinical applications. Tα1 can enha...

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Main Authors: Li, Weina, Song, Liqiang, Wu, Shouzhen, Xue, Xiaochang, Zhang, Lu, He, Liqing, Han, Wei, Wang, Qing, Ling, Rui, Zhang, Wei, Yan, Zhen, Zhang, Yingqi
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2011
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107470/
https://ncbi.nlm.nih.gov/pubmed/21647330
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