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Nucleolar disruption and apoptosis are distinct neuronal responses to etoposide-induced DNA damage
While DNA damaging topoisomerase inhibitors induce apoptosis in developing neurons, their effects on adult neurons have not yet been characterized. We report a blockage of RNA-Polymerase-1-driven transcription and nucleolar stress in neocortical neurons of adult rats after intracarotid injection of...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107349/ https://ncbi.nlm.nih.gov/pubmed/21517844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07279.x |
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