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Agonist trapped in ATP-binding sites of the P2X2 receptor
ATP-gated P2X receptors are trimeric ion channels, as recently confirmed by X-ray crystallography. However, the structure was solved without ATP and even though extracellular intersubunit cavities surrounded by conserved amino acid residues previously shown to be important for ATP function were prop...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107266/ https://ncbi.nlm.nih.gov/pubmed/21576497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102170108 |
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