Agonist trapped in ATP-binding sites of the P2X2 receptor

ATP-gated P2X receptors are trimeric ion channels, as recently confirmed by X-ray crystallography. However, the structure was solved without ATP and even though extracellular intersubunit cavities surrounded by conserved amino acid residues previously shown to be important for ATP function were prop...

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Detaylı Bibliyografya
Asıl Yazarlar: Jiang, Ruotian, Lemoine, Damien, Martz, Adeline, Taly, Antoine, Gonin, Sophie, Prado de Carvalho, Lia, Specht, Alexandre, Grutter, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107266/
https://ncbi.nlm.nih.gov/pubmed/21576497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102170108
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