p53 Transactivation and the Impact of Mutations, Cofactors and Small Molecules Using a Simplified Yeast-Based Screening System

BACKGROUND: The p53 tumor suppressor, which is altered in most cancers, is a sequence-specific transcription factor that is able to modulate the expression of many target genes and influence a variety of cellular pathways. Inactivation of the p53 pathway in cancer frequently occurs through the expre...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Andreotti, Virginia, Ciribilli, Yari, Monti, Paola, Bisio, Alessandra, Lion, Mattia, Jordan, Jennifer, Fronza, Gilberto, Menichini, Paola, Resnick, Michael A., Inga, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107237/
https://ncbi.nlm.nih.gov/pubmed/21674059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020643
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker